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5-Azacytidine Can Induce Lethal Mutagenesis in Human Immunodeficiency Virus Type 1
Ribonucleosides inhibit human immunodeficiency virus type 1 (HIV-1) replication by mechanisms that have not been fully elucidated. Here, we report the antiviral mechanism for the ribonucleoside analog 5-azacytidine (5-AZC). We hypothesized that the anti-HIV-1 activity of 5-AZC was due to an increase...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2772699/ https://ncbi.nlm.nih.gov/pubmed/19726509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01406-09 |
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