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Back to the future: revisiting HIV-1 lethal mutagenesis
The concept of eliminating HIV-1 infectivity by elevating the viral mutation rate was first proposed over a decade ago, even though the general concept had been conceived earlier for RNA viruses. Lethal mutagenesis was originally viewed as a novel chemotherapeutic approach for treating HIV-1 infecti...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565075/ https://ncbi.nlm.nih.gov/pubmed/23195922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2012.10.006 |
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