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Interrelationship between HIV-1 Fitness and Mutation Rate

Differences in replication fidelity, as well as mutator and antimutator strains, suggest that virus mutation rates are heritable and prone to natural selection. Human immunodeficiency virus type 1 (HIV-1) has many distinct advantages for the study of mutation rate optimization given the wealth of st...

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Detalhes bibliográficos
Main Authors: Dapp, Michael J., Heineman, Richard H., Mansky, Louis M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534800/
https://ncbi.nlm.nih.gov/pubmed/23084856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.10.009
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