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The HIV-1 Reverse Transcriptase A62V Mutation Influences Replication Fidelity and Viral Fitness in the Context of Multi-Drug-Resistant Mutations

Emergence of human immunodeficiency virus type 1 (HIV-1) drug resistance arises from mutation fixation in the viral genome during antiretroviral therapy. Primary mutations directly confer antiviral drug resistance, while secondary mutations arise that do not confer drug resistance. The A62V amino ac...

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書目詳細資料
發表在:Viruses
Main Authors: Maldonado, José O., Mansky, Louis M.
格式: Artigo
語言:Inglês
出版: MDPI 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070896/
https://ncbi.nlm.nih.gov/pubmed/30029500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10070376
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