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Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases

Retroviruses are RNA viruses that replicate through a DNA intermediate, in a process catalyzed by the viral reverse transcriptase (RT). Although cellular polymerases and host factors contribute to retroviral mutagenesis, the RT errors play a major role in retroviral mutation. RT mutations that affec...

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Detalhes bibliográficos
Autor principal: Menéndez-Arias, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185545/
https://ncbi.nlm.nih.gov/pubmed/21994586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v1031137
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