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In vivo mutation rates and the landscape of fitness costs of HIV-1
Mutation rates and fitness costs of deleterious mutations are difficult to measure in vivo but essential for a quantitative understanding of evolution. Using whole genome deep sequencing data from longitudinal samples during untreated HIV-1 infection, we estimated mutation rates and fitness costs in...
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| Publicado no: | Virus Evol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5399928/ https://ncbi.nlm.nih.gov/pubmed/28458914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ve/vex003 |
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