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Discovery of Novel Ribonucleoside Analogs with Activity against Human Immunodeficiency Virus Type 1

Reverse transcription is an important early step in retrovirus replication and is a key point targeted by evolutionarily conserved host restriction factors (e.g., APOBEC3G, SamHD1). Human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) is a major target of antiretroviral drugs, and...

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Detalhes bibliográficos
Main Authors: Dapp, Michael J., Bonnac, Laurent, Patterson, Steven E., Mansky, Louis M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911745/
https://ncbi.nlm.nih.gov/pubmed/24155391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02444-13
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