Mutant Huntingtin Impairs Vesicle Formation from Recycling Endosomes by Interfering with Rab11 Activity

Huntingtin (Htt) localizes to endosomes, but its role in the endocytic pathway is not established. Recently, we found that Htt is important for the activation of Rab11, a GTPase involved in endosomal recycling. Here we studied fibroblasts of healthy individuals and patients with Huntington's di...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Li, Xueyi, Standley, Clive, Sapp, Ellen, Valencia, Antonio, Qin, Zheng-Hong, Kegel, Kimberly B., Yoder, Jennifer, Comer-Tierney, Laryssa A., Esteves, Miguel, Chase, Kathryn, Alexander, Jonathan, Masso, Nicholas, Sobin, Lindsay, Bellve, Karl, Tuft, Richard, Lifshitz, Lawrence, Fogarty, Kevin, Aronin, Neil, DiFiglia, Marian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2009
Aiheet:
Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772576/
https://ncbi.nlm.nih.gov/pubmed/19752198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00420-09
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia