Mutant Huntingtin Impairs Vesicle Formation from Recycling Endosomes by Interfering with Rab11 Activity

Huntingtin (Htt) localizes to endosomes, but its role in the endocytic pathway is not established. Recently, we found that Htt is important for the activation of Rab11, a GTPase involved in endosomal recycling. Here we studied fibroblasts of healthy individuals and patients with Huntington's di...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Xueyi, Standley, Clive, Sapp, Ellen, Valencia, Antonio, Qin, Zheng-Hong, Kegel, Kimberly B., Yoder, Jennifer, Comer-Tierney, Laryssa A., Esteves, Miguel, Chase, Kathryn, Alexander, Jonathan, Masso, Nicholas, Sobin, Lindsay, Bellve, Karl, Tuft, Richard, Lifshitz, Lawrence, Fogarty, Kevin, Aronin, Neil, DiFiglia, Marian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2009
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772576/
https://ncbi.nlm.nih.gov/pubmed/19752198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00420-09
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg