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Adaptation of topoisomerase I paralogs to nuclear and mitochondrial DNA
Topoisomerase I is essential for DNA metabolism in nuclei and mitochondria. In yeast, a single topoisomerase I gene provides for both organelles. In vertebrates, topoisomerase I is divided into nuclear and mitochondrial paralogs (Top1 and Top1mt). To assess the meaning of this gene duplication, we t...
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| Autors principals: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770673/ https://ncbi.nlm.nih.gov/pubmed/19720733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp708 |
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