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Targeted gene conversion induced by triplex-directed psoralen interstrand crosslinks in mammalian cells

Correction of a defective gene is a promising approach for both basic research and clinical gene therapy. However, the absence of site-specific targeting and the low efficiency of homologous recombination in human cells present barriers to successful gene targeting. In an effort to overcome these ba...

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Detalhes bibliográficos
Main Authors: Liu, Yaobin, Nairn, Rodney S., Vasquez, Karen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770658/
https://ncbi.nlm.nih.gov/pubmed/19726585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp678
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