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Efficient processing of TFO-directed psoralen DNA interstrand crosslinks by the UvrABC nuclease
Photoreactive psoralens can form interstrand crosslinks (ICLs) in double-stranded DNA. In eubacteria, the endonuclease UvrABC plays a key role in processing psoralen ICLs. Psoralen-modified triplex-forming oligonucleotides (TFOs) can be used to direct ICLs to specific genomic sites. Previous studies...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2602775/ https://ncbi.nlm.nih.gov/pubmed/18996898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn880 |
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