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HMGB1 interacts with XPA to facilitate the processing of DNA interstrand crosslinks in human cells

Many effective agents used in cancer chemotherapy cause DNA interstrand crosslinks (ICLs), which covalently link both strands of the double helix together resulting in cytotoxicity. ICLs are thought to be processed by proteins from a variety of DNA repair pathways; however, a clear understanding of...

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Foilsithe in:Nucleic Acids Res
Main Authors: Mukherjee, Anirban, Vasquez, Karen M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756816/
https://ncbi.nlm.nih.gov/pubmed/26578599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1183
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