Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks

DNA interstrand crosslinks (ICLs) are among the most cytotoxic types of DNA damage, thus ICL-inducing agents such as psoralen, are clinically useful chemotherapeutics. Psoralen-modified triplex-forming oligonucleotides (TFOs) have been used to target ICLs to specific genomic sites to increase the se...

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Hlavní autoři: Zhao, Junhua, Jain, Aklank, Iyer, Ravi R., Modrich, Paul L., Vasquez, Karen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715249/
https://ncbi.nlm.nih.gov/pubmed/19468048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp399
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