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HMGB1 interacts with XPA to facilitate the processing of DNA interstrand crosslinks in human cells
Many effective agents used in cancer chemotherapy cause DNA interstrand crosslinks (ICLs), which covalently link both strands of the double helix together resulting in cytotoxicity. ICLs are thought to be processed by proteins from a variety of DNA repair pathways; however, a clear understanding of...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4756816/ https://ncbi.nlm.nih.gov/pubmed/26578599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1183 |
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