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Human XPC-hHR23B interacts with XPA-RPA in the recognition of triplex-directed psoralen DNA interstrand crosslinks

DNA interstrand crosslinks (ICLs) represent a severe form of damage that blocks DNA metabolic processes and can lead to cell death or carcinogenesis. The repair of DNA ICLs in mammals is not well characterized. We have reported previously that a key protein complex of nucleotide excision repair (NER...

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Detalhes bibliográficos
Main Authors: Thoma, Brian S., Wakasugi, Mitsuo, Christensen, Jesper, Reddy, Madhava C., Vasquez, Karen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140082/
https://ncbi.nlm.nih.gov/pubmed/15914671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki610
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