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Human XPC-hHR23B interacts with XPA-RPA in the recognition of triplex-directed psoralen DNA interstrand crosslinks

DNA interstrand crosslinks (ICLs) represent a severe form of damage that blocks DNA metabolic processes and can lead to cell death or carcinogenesis. The repair of DNA ICLs in mammals is not well characterized. We have reported previously that a key protein complex of nucleotide excision repair (NER...

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Hlavní autoři: Thoma, Brian S., Wakasugi, Mitsuo, Christensen, Jesper, Reddy, Madhava C., Vasquez, Karen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140082/
https://ncbi.nlm.nih.gov/pubmed/15914671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki610
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