GENE TRANSFER OF INDUCIBLE NITRIC OXIDE SYNTHASE AFFORDS CARDIOPROTECTION BY UPREGULATING HEME OXYGENASE-1 VIA AN NF-κB-DEPENDENT PATHWAY

BACKGROUND: Although inducible nitric oxide synthase (iNOS) is known to impart powerful protection against myocardial infarction, the mechanism for this salubrious action remains unclear. METHODS AND RESULTS: Adenovirus-mediated iNOS gene transfer in mice resulted, 48-72 h later, in increased expres...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Li, Qianhong, Guo, Yiru, Ou, Qinghui, Cui, Chuanjue, Wu, Wen-Jian, Tan, Wei, Zhu, Xiaoping, Lanceta, Lilibeth B, Sanganalmath, Santosh K., Dawn, Buddhadeb, Shinmura, Ken, Rokosh, Gregg D., Wang, Shuyan, Bolli, Roberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768612/
https://ncbi.nlm.nih.gov/pubmed/19752329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.778688
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge