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How Heme Oxygenase-1 Prevents Heme-Induced Cell Death

Earlier observations indicate that free heme is selectively toxic to cells lacking heme oxygenase-1 (HO-1) but how this enzyme prevents heme toxicity remains unexplained. Here, using A549 (human lung cancer) and immortalized human bronchial epithelial cells incubated with exogenous heme, we find kno...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Lanceta, Lilibeth, Mattingly, Jacob M., Li, Chi, Eaton, John W.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535878/
https://ncbi.nlm.nih.gov/pubmed/26270345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134144
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