CARDIOPROTECTIVE AND ANTI-APOPTOTIC EFFECTS OF HEME OXYGENASE-1 IN THE FAILING HEART

BACKGROUND: Heme oxygenase-1 (HO-1) is an inducible stress-response protein that imparts antioxidant and anti-apoptotic effects. However, its pathophysiological role in cardiac remodeling and chronic heart failure (HF) is unknown. We hypothesized that induction of HO-1 in HF ameliorates pathological...

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Autori principali: Wang, Guangwu, Hamid, Tariq, Keith, Rachel J., Zhou, Guihua, Partridge, Charles R., Xiang, Xilin, Kingery, Justin R., Lewis, Robert K., Li, Qianhong, Rokosh, D. Gregg, Ford, Rachael, Spinale, Francis G., Riggs, Daniel W., Srivastava, Sanjay, Bhatnagar, Aruni, Bolli, Roberto, Prabhu, Sumanth D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917269/
https://ncbi.nlm.nih.gov/pubmed/20404253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.905471
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