CARDIOPROTECTIVE AND ANTI-APOPTOTIC EFFECTS OF HEME OXYGENASE-1 IN THE FAILING HEART

BACKGROUND: Heme oxygenase-1 (HO-1) is an inducible stress-response protein that imparts antioxidant and anti-apoptotic effects. However, its pathophysiological role in cardiac remodeling and chronic heart failure (HF) is unknown. We hypothesized that induction of HO-1 in HF ameliorates pathological...

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Detalhes bibliográficos
Main Authors: Wang, Guangwu, Hamid, Tariq, Keith, Rachel J., Zhou, Guihua, Partridge, Charles R., Xiang, Xilin, Kingery, Justin R., Lewis, Robert K., Li, Qianhong, Rokosh, D. Gregg, Ford, Rachael, Spinale, Francis G., Riggs, Daniel W., Srivastava, Sanjay, Bhatnagar, Aruni, Bolli, Roberto, Prabhu, Sumanth D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917269/
https://ncbi.nlm.nih.gov/pubmed/20404253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.905471
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