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TNF receptor signaling inhibits cardiomyogenic differentiation of cardiac stem cells and promotes a neuroadrenergic-like fate
Despite expansion of resident cardiac stem cells (CSCs; c-kit(+)Lin(−)) after myocardial infarction, endogenous repair processes are insufficient to prevent adverse cardiac remodeling and heart failure (HF). This suggests that the microenvironment in post-ischemic and failing hearts compromises CSC...
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| Publicat a: | Am J Physiol Heart Circ Physiol |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5130488/ https://ncbi.nlm.nih.gov/pubmed/27591224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00904.2015 |
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