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TNF receptor signaling inhibits cardiomyogenic differentiation of cardiac stem cells and promotes a neuroadrenergic-like fate

Despite expansion of resident cardiac stem cells (CSCs; c-kit(+)Lin(−)) after myocardial infarction, endogenous repair processes are insufficient to prevent adverse cardiac remodeling and heart failure (HF). This suggests that the microenvironment in post-ischemic and failing hearts compromises CSC...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Hamid, Tariq, Xu, Yuanyuan, Ismahil, Mohamed Ameen, Li, Qianhong, Jones, Steven P., Bhatnagar, Aruni, Bolli, Roberto, Prabhu, Sumanth D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130488/
https://ncbi.nlm.nih.gov/pubmed/27591224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00904.2015
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