Activated T-Lymphocytes are Essential Drivers of Pathological Remodeling in Ischemic Heart Failure

BACKGROUND: Inappropriately sustained inflammation is a hallmark of chronic ischemic heart failure (HF); however, the pathophysiological role of T-lymphocytes is unclear. METHODS AND RESULTS: Permanent coronary ligation was performed in adult C57BL/6 mice. As compared with sham-operated mice, mice w...

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Veröffentlicht in:Circ Heart Fail
Hauptverfasser: Bansal, Shyam S., Ismahil, Mohamed Ameen, Goel, Mehak, Patel, Bindiya, Hamid, Tariq, Rokosh, Gregg, Prabhu, Sumanth D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331621/
https://ncbi.nlm.nih.gov/pubmed/28242779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.116.003688
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