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DYSFUNCTIONAL AND PRO-INFLAMMATORY REGULATORY T-LYMPHOCYTES ARE ESSENTIAL FOR ADVERSE CARDIAC REMODELING IN ISCHEMIC CARDIOMYOPATHY

BACKGROUND. Heart failure (HF) is a state of inappropriately sustained inflammation, suggesting the loss of normal immunosuppressive mechanisms. Regulatory T-lymphocytes (Tregs) are considered key suppressors of immune responses; however, their role in HF is unknown. We hypothesized that Tregs are d...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Bansal, Shyam S., Ismahil, Mohamed Ameen, Goel, Mehak, Zhou, Guihua, Rokosh, Gregg, Hamid, Tariq, Prabhu, Sumanth D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322956/
https://ncbi.nlm.nih.gov/pubmed/30586716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.118.036065
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