Leukocyte iNOS is required for inflammation and pathological remodeling in ischemic heart failure

In the failing heart, iNOS is expressed by both macrophages and cardiomyocytes. We hypothesized that inflammatory cell-localized iNOS exacerbates left ventricular (LV) remodeling. Wild-type (WT) C57BL/6 mice underwent total body irradiation and reconstitution with bone marrow from iNOS(−/−) mice (iN...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Basic Res Cardiol
Main Authors: Kingery, Justin R., Hamid, Tariq, Lewis, Robert K., Ismahil, Mohamed Ameen, Bansal, Shyam S., Rokosh, Gregg, Townes, Tim M., Ildstad, Suzanne T., Jones, Steven P., Prabhu, Sumanth D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555149/
https://ncbi.nlm.nih.gov/pubmed/28238121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-017-0609-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados