Leukocyte iNOS is required for inflammation and pathological remodeling in ischemic heart failure

In the failing heart, iNOS is expressed by both macrophages and cardiomyocytes. We hypothesized that inflammatory cell-localized iNOS exacerbates left ventricular (LV) remodeling. Wild-type (WT) C57BL/6 mice underwent total body irradiation and reconstitution with bone marrow from iNOS(−/−) mice (iN...

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Dades bibliogràfiques
Publicat a:Basic Res Cardiol
Autors principals: Kingery, Justin R., Hamid, Tariq, Lewis, Robert K., Ismahil, Mohamed Ameen, Bansal, Shyam S., Rokosh, Gregg, Townes, Tim M., Ildstad, Suzanne T., Jones, Steven P., Prabhu, Sumanth D.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555149/
https://ncbi.nlm.nih.gov/pubmed/28238121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-017-0609-2
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