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DYSFUNCTIONAL AND PRO-INFLAMMATORY REGULATORY T-LYMPHOCYTES ARE ESSENTIAL FOR ADVERSE CARDIAC REMODELING IN ISCHEMIC CARDIOMYOPATHY
BACKGROUND. Heart failure (HF) is a state of inappropriately sustained inflammation, suggesting the loss of normal immunosuppressive mechanisms. Regulatory T-lymphocytes (Tregs) are considered key suppressors of immune responses; however, their role in HF is unknown. We hypothesized that Tregs are d...
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| Pubblicato in: | Circulation |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6322956/ https://ncbi.nlm.nih.gov/pubmed/30586716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.118.036065 |
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