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Focal striatal dopamine may potentiate dyskinesias in parkinsonian monkeys
Striatal neurons convert l-dopa to dopamine (DA) following gene transfer of aromatic l-amino acid decarboxylase (AADC) via adeno-associated virus (AAV) in parkinsonian monkeys. We investigated whether AAV-AADC could reduce or eliminate l-dopa-induced dyskinesias (LIDs) and side effects in MPTP-treat...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2766604/ https://ncbi.nlm.nih.gov/pubmed/16337943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2005.10.022 |
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