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Nicotinamidase modulation of NAD(+) biosynthesis and nicotinamide levels separately affect reproductive development and cell survival in C. elegans
Nicotinamide adenine dinucleotide (NAD(+)) is a central molecule in cellular metabolism and an obligate co-substrate for NAD(+)-consuming enzymes, which regulate key biological processes such as longevity and stress responses. Although NAD(+) biosynthesis has been intensely studied, little analysis...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Company of Biologists
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761111/ https://ncbi.nlm.nih.gov/pubmed/19820182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.028431 |
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