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An NAD(+) biosynthetic pathway enzyme functions cell non-autonomously in C. elegans development
BACKGROUND: Disruption of cellular metabolite levels can adversely impact development. Specifically, loss-of-function of the C. elegans NAD(+) salvage biosynthesis gene PNC-1 results in an array of developmental phenotypes. Intriguingly, PNC-1 and its functional equivalent in vertebrates are secrete...
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| Publicado no: | Dev Dyn |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5245173/ https://ncbi.nlm.nih.gov/pubmed/24753121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24139 |
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