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Uridine monophosphate synthetase enables eukaryotic de novo NAD(+) biosynthesis from quinolinic acid
NAD(+) biosynthesis is an attractive and promising therapeutic target for influencing health span and obesity-related phenotypes as well as tumor growth. Full and effective use of this target for therapeutic benefit requires a complete understanding of NAD(+) biosynthetic pathways. Here, we report a...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5500784/ https://ncbi.nlm.nih.gov/pubmed/28559281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C117.795344 |
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