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Nicotinamidase modulation of NAD(+) biosynthesis and nicotinamide levels separately affect reproductive development and cell survival in C. elegans
Nicotinamide adenine dinucleotide (NAD(+)) is a central molecule in cellular metabolism and an obligate co-substrate for NAD(+)-consuming enzymes, which regulate key biological processes such as longevity and stress responses. Although NAD(+) biosynthesis has been intensely studied, little analysis...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Company of Biologists
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761111/ https://ncbi.nlm.nih.gov/pubmed/19820182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.028431 |
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