Characterization of Nicotinamidases: Steady-State Kinetic Parameters, Class-wide Inhibition by Nicotinaldehydes and Catalytic Mechanism

Nicotinamidases are metabolic enzymes that hydrolyze nicotinamide to nicotinic acid. These enzymes are widely distributed across biology, with examples found encoded in the genomes of Mycobacteria, Archaea, Eubacteria, Protozoa, yeast and invertebrates but there are none found in mammals. Although r...

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Hlavní autoři: French, Jarrod B., Cen, Yana, Vrablik, Tracy L., Xu, Ping, Allen, Eleanor, Hanna-Rose, Wendy, Sauve, Anthony A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010197/
https://ncbi.nlm.nih.gov/pubmed/20979384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1012518
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