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Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease
Sequence-specific endonucleases recognizing long target sequences are emerging as powerful tools for genome engineering. These endonucleases could be used to correct deleterious mutations or to inactivate viruses, in a new approach to molecular medicine. However, such applications are highly demandi...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760784/ https://ncbi.nlm.nih.gov/pubmed/19584299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp548 |
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