A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences

Meganucleases, or homing endonucleases (HEs) are sequence-specific endonucleases with large (>14 bp) cleavage sites that can be used to induce efficient homologous gene targeting in cultured cells and plants. These findings have opened novel perspectives for genome engineering in a wide range of...

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Detalhes bibliográficos
Main Authors: Smith, Julianne, Grizot, Sylvestre, Arnould, Sylvain, Duclert, Aymeric, Epinat, Jean-Charles, Chames, Patrick, Prieto, Jesús, Redondo, Pilar, Blanco, Francisco J., Bravo, Jerónimo, Montoya, Guillermo, Pâques, Frédéric, Duchateau, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1702487/
https://ncbi.nlm.nih.gov/pubmed/17130168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl720
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