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In vivo selection of engineered homing endonucleases using double-strand break induced homologous recombination

Homing endonucleases, endonucleases capable of recognizing long DNA sequences, have been shown to be a tool of choice for precise and efficient genome engineering. Consequently, the possibility to engineer novel endonucleases with tailored specificities is under strong investigation. In this report,...

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Detalhes bibliográficos
Main Authors: Chames, Patrick, Epinat, Jean-Charles, Guillier, Sophie, Patin, Amélie, Lacroix, Emmanuel, Pâques, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1289081/
https://ncbi.nlm.nih.gov/pubmed/16306233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni175
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