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Effect of double-strand breaks on homologous recombination in mammalian cells and extracts.

We examined the effect of double-strand breaks on homologous recombination between two plasmids in human cells and in nuclear extracts prepared from human and rodent cells. Two pSV2neo plasmids containing nonreverting, nonoverlapping deletions were cotransfected into cells or incubated with cell ext...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Song, K Y, Chekuri, L, Rauth, S, Ehrlich, S, Kucherlapati, R
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1985
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369160/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3870133/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.5.12.3331
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