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Discovery and development of heat shock protein 90 inhibitors

Heat shock protein 90 (Hsp90) is an important target in cancer because of its role in maintaining transformation and has recently become the focus of several drug discovery and development efforts. While compounds with different modes of action are known, the focus of this review is on those classes...

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Bibliografische gegevens
Hoofdauteurs: Taldone, Tony, Sun, Weilin, Chiosis, Gabriela
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760286/
https://ncbi.nlm.nih.gov/pubmed/19017562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.10.087
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