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Discovery and development of heat shock protein 90 inhibitors

Heat shock protein 90 (Hsp90) is an important target in cancer because of its role in maintaining transformation and has recently become the focus of several drug discovery and development efforts. While compounds with different modes of action are known, the focus of this review is on those classes...

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Detalhes bibliográficos
Main Authors: Taldone, Tony, Sun, Weilin, Chiosis, Gabriela
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760286/
https://ncbi.nlm.nih.gov/pubmed/19017562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.10.087
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