Loading...

The NLRP3 Inflammasome is Critical for Alum-Mediated IL-1β Secretion but Dispensable for Adjuvant Activity

Alum (aluminiun hydroxide) is the most widely used adjuvant in human vaccines, but the immune mechanisms that are activated by alum remain poorly understood. Alum has been recently shown to promote caspase-1 activation and IL-1β secretion but the cellular pathways involved remain elusive. Here we re...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Franchi, Luigi, Núñez, Gabriel
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759997/
https://ncbi.nlm.nih.gov/pubmed/18624356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838549
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!