A critical role for hemolysin in Vibrio fluvialis-induced IL-1β secretion mediated by the NLRP3 inflammasome in macrophages

Vibrio fluvialis causes human diarrhea, but the pathogenesis is not well-studied. We hypothesized that V. fluvialis-secreted hemolysin (VFH) may induce IL-1β secretion through the activation of the NLRP3 inflammasome and contribute to the pathogenicity of V. fluvialis. To examine this possibility, w...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Song, Liqiong, Huang, Yuanming, Zhao, Meng, Wang, Zhihao, Wang, Shujing, Sun, Hui, Kan, Biao, Meng, Guangxun, Liang, Weili, Ren, Zhihong
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440915/
https://ncbi.nlm.nih.gov/pubmed/26052324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.00510
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