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The Protein Kinase PKR is Critical for LPS-induced iNOS Production, but Dispensable for Inflammasome Activation in Macrophages
The inflammasomes are multi-protein platforms that drive the activation of caspase-1 leading to the processing and secretion of biologically active IL-1β and IL-18. Different inflammasomes including NLRP3, NLRC4 and AIM2 are activated and assembled in response to distinct microbial or endogenous sti...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3757543/ https://ncbi.nlm.nih.gov/pubmed/23401008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243187 |
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