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PPARα agonists inhibit nitric oxide production by enhancing iNOS degradation in LPS-treated macrophages
BACKGROUND AND PURPOSE: Nitric oxide (NO) production through the inducible nitric oxide synthase (iNOS) pathway is increased in response to pro-inflammatory cytokines and bacterial products. In inflammation, NO has pro-inflammatory and regulatory effects. Peroxisome proliferator-activated receptors...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2095111/ https://ncbi.nlm.nih.gov/pubmed/17891158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707477 |
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