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Investigating the Role of TNF-α and IFN-γ Activation on the Dynamics of iNOS Gene Expression in LPS Stimulated Macrophages

Macrophage produced inducible nitric oxide synthase (iNOS) is known to play a critical role in the proinflammatory response against intracellular pathogens by promoting the generation of bactericidal reactive nitrogen species. Robust and timely production of nitric oxide (NO) by iNOS and analogous p...

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Pubblicato in:PLoS One
Autori principali: Salim, Taha, Sershen, Cheryl L., May, Elebeoba E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898755/
https://ncbi.nlm.nih.gov/pubmed/27276061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153289
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