Nalaganje...
Synthesis and investigations of double-pharmacophore ligands for treatment of chronic and neuropathic pain
Acids 9 a–f as possible bivalent ligands designed as a structural combination of opioid μ-agonist (Fentanyl) and NSAID (Indomethacin) activities and produced compounds which were tested as analgesics. The obtained series of compounds exhibits low affinity and activity both at opioid receptors and as...
Shranjeno v:
| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2759397/ https://ncbi.nlm.nih.gov/pubmed/19540763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.05.065 |
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