Loading...
Increased radio-resistance and accelerated B-cell lymphomas in mice with Mdmx mutations that prevent modifications by DNA damage-activated kinases
Mdmx is a critical negative regulator of the p53 pathway that is stoichiometrically limiting in some tissues. Post-translational modification and degradation of Mdmx after DNA damage have been proposed to be essential for p53 activation. We tested this model in vivo, where critical stoichiometric re...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2758524/ https://ncbi.nlm.nih.gov/pubmed/19573810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.05.008 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|