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Functions of MDMX in the Modulation of the p53-Response

The MDM family proteins MDM2 and MDMX are two critical regulators of the p53 tumor suppressor protein. Expression of both proteins is necessary for allowing the embryonal development by keeping the activity of p53 in check. Upon stresses that need to activate p53 to perform its function as guardian...

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Autori principali: Lenos, Kristiaan, Jochemsen, Aart G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085504/
https://ncbi.nlm.nih.gov/pubmed/21541195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/876173
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