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In Vivo RNAi Screening Identifies Regulators of Actin Dynamics as Key Determinants of Lymphoma Progression

Mouse models have dramatically improved our understanding of cancer development and tumor biology. However, these models have shown limited efficacy as tractable systems for unbiased genetic experimentation. Here, we report the adaptation of loss of function screening to mouse models of cancer. Spec...

詳細記述

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書誌詳細
主要な著者: Meacham, Corbin E., Ho, Emily E., Dubrovsky, Esther, Gertler, Frank B., Hemann, Michael T.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756700/
https://ncbi.nlm.nih.gov/pubmed/19783987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.451
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