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In Vivo RNAi Screening Identifies Regulators of Actin Dynamics as Key Determinants of Lymphoma Progression

Mouse models have dramatically improved our understanding of cancer development and tumor biology. However, these models have shown limited efficacy as tractable systems for unbiased genetic experimentation. Here, we report the adaptation of loss of function screening to mouse models of cancer. Spec...

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Detalhes bibliográficos
Main Authors: Meacham, Corbin E., Ho, Emily E., Dubrovsky, Esther, Gertler, Frank B., Hemann, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756700/
https://ncbi.nlm.nih.gov/pubmed/19783987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.451
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