A Global In Vivo Drosophila RNAi Screen Identifies a Key Role of Ceramide Phosphoethanolamine for Glial Ensheathment of Axons

Glia are of vital importance for all complex nervous system. One of the many functions of glia is to insulate and provide trophic and metabolic support to axons. Here, using glial-specific RNAi knockdown in Drosophila, we silenced 6930 conserved genes in adult flies to identify essential genes and p...

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Detalhes bibliográficos
Main Authors: Ghosh, Aniket, Kling, Tina, Snaidero, Nicolas, Sampaio, Julio L., Shevchenko, Andrej, Gras, Heribert, Geurten, Bart, Göpfert, Martin C., Schulz, Jörg B., Voigt, Aaron, Simons, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861124/
https://ncbi.nlm.nih.gov/pubmed/24348263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003980
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