Carnitine Insufficiency Caused by Aging and Overnutrition Compromises Mitochondrial Performance and Metabolic Control

In addition to its essential role in permitting mitochondrial import and oxidation of long chain fatty acids, carnitine also functions as an acyl group acceptor that facilitates mitochondrial export of excess carbons in the form of acylcarnitines. Recent evidence suggests carnitine requirements incr...

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Detalhes bibliográficos
Main Authors: Noland, Robert C., Koves, Timothy R., Seiler, Sarah E., Lum, Helen, Lust, Robert M., Ilkayeva, Olga, Stevens, Robert D., Hegardt, Fausto G., Muoio, Deborah M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Metabolism and Bioenergetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755692/
https://ncbi.nlm.nih.gov/pubmed/19553674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.032888
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